LEGEND-T2DM Disclosures

  • This protocol is undertaken within Observational Health Data Sciences and Informatics (OHDSI), an open collaboration.

  • MAS receives grant funding from the US National Institutes of Health, the US Department of Veterans Affairs and the US Food & Drug Administration and contracts from Janssen Research.

  • MJS and PBR are employees of Janssen Research and Development and shareholders in John & Johnson.

  • GH receives grant funding from the US National Institutes of Health and the US Food & Drug Administration and contracts from Janssen Research and Development.

  • HMK receives grants from the US Food & Drug Administration, Medtronics and Janssen Research and Development, is co-founder of HugoHealth and chairs the Cardiac Scientific Advisory Board for UnitedHealth.

  • RK is a founder of Evidence2Health, and receives grant funding from the US National Institutes of Health, Doris Duke Charitable Foundation, and Bristol-Myers Squibb.



LEGEND-T2DM Protocol:

Khera, Rohan, Martijn J. Schuemie, Yuan Lu, Anna Ostropolets, RuiJun Chen, George Hripcsak, Patrick B. Ryan, Harlan M. Krumholz, and Marc A. Suchard. "Protocol: Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world comparative cardiovascular effectiveness and safety studies." BMJ Open 12, no. 6 (2022).

https://bmjopen.bmj.com/content/12/6/e057977.long